Single-molecule chromatin tracing reveals a diversity of megabase heterochromatin domains.
Chromosomes fold into distinct domains that regulate transcription, replication and repair. In addition to well-characterized topologically associating domains (TADs) and compartments, the diversity of heterochromatin domains remains poorly defined at the sequence level. Here, using single-molecule tracing of nascent h...
Dania Camila Pulido Barrera, J. E. You, Angelo L. Angonezi et al.
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