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Susmita Ghosh

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#protein folding Sep 2026

Replication protein A1 from L. donovani interacts with RECQb via the C-terminal OB fold and stimulates its helicase activity on branched substrates.

The results reveal a new C-terminus-mediated RPA-RecQ interaction in L. donovani that resembles the prokaryotic SSB-RecQ interaction mechanism, while maintaining functional conservation of eukaryotic DNA metabolism.

Mayukh Chakraborty, Susmita Ghosh, Surasree Chakraborty et al. · 0 citations

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