INTRODUCTION
Leishmania sp. can cause visceral, mucosal, cutaneous, and subcutaneous forms. Leishmania major is responsible for the cutaneous manifestation of the disease. Due to the limited treatment options and growing resistance in the disease, an in-silico study was conducted to find new therapeutic targets in L. m...
Chandra Kanta Bhusal, Upninder Kaur, Davinder Kaur et al.· Infectious Diseases - Drug T...· 0 citations
This review revisits algorithms, tools, and workflows for sequence and phylogenetic analysis in the NGS-based omics era, with a focus on comparative performance and scenario-driven decision-making.
Abhishek Kumar, T. C. Dakal, Kayenat Parveen et al.· Biochemical Genetics· 0 citations
TP53 and FOXA1 mutations, observed in primary and metastatic castration-resistant prostate cancer, were associated with aggressive disease phenotypes and potential therapeutic resistance, and these findings highlight TP53 and FOXA1 as promising biomarkers and potential therapeutic targets in prostate cancer.
This review traces how heavy metals including Pb, Cd, As, Hg, Cr and Ni along with pesticide residues enter medicinal plants, disrupt their physiology, impair secondary metabolite production and ultimately reach human consumers.
P. Shukla, P. Gupta, Arpit Singh et al.· Biometals· 0 citations
Unraveling the intricate mechanisms of EMT activation in cancer will contribute to the advancement of personalized medicine and the design of more effective treatments against metastatic disease and pave the way for advancements in personalized medicine and improved treatment strategies for patients affected by EMT-rel...
Vafa Meftahpour, T. C. Dakal, Jarek Maciaczyk et al.· Signal Transduction and Targ...· 0 citations
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