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Author

T. Lashley

3 papers indexed here

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Review Open access Sep 2026

White matter dysfunction in Alzheimer’s disease: a convergence or divergence of hypotheses

Alzheimer’s disease (AD) is a multifactorial disease with several key hypotheses centred around its pathological hallmarks, including amyloid and tau and other mechanisms, such as vascular dysfunction. Revised criteria for AD diagnosis reflects these hypotheses and includes white matter hyperintensities (WMH) as a bi...

N. Rambarack, T. Lashley, Josephine Barnes et al. · 0 citations
Open access Aug 2026

Amyloidogenic Amylin Signaling Links Diabetes to Dementia Pathogenesis

Selective targeting of circulating amyloidogenic amylin and its pathogenic signaling may enable biomarker development and disease-modifying therapies, and enable biomarker development and disease-modifying therapies.

F. Despa, T. Lashley · 0 citations
Open access Jul 2026

Altered synaptic and astrocytic proteins in Lewy body disorders associated with GBA mutations

This study is the first to validate several synaptic markers in human post-mortem-associated GBA N370S mutation suggesting the potential role of GBA gene due to mutations which could alter the levels of some synaptic markers.

Thamir M. Eid, T. Lashley, Thomas T. Warner et al. · 0 citations

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