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T. Olender

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Open access Oct 2026

A massively parallel reporter screen defines the syntax of SECReTE, a secretion-enhancing cis regulatory targeting element, in mammalian cells

Messenger RNA (mRNA) localization to specific subcellular regions is crucial for proper protein translation and localization. Potential means to localize mRNAs include cis-acting or structural motifs embedded within the sequence. We previously identified a secretion-enhancing cis regulatory targeting element (SECReTE)...

Gal Haimovich, Gabriela Lobinsky, Shu-Ting You et al. · 0 citations
Open access Aug 2026

RTTN moonlights beyond the centrosome to control ribosome biogenesis and tRNA modification in human brain organoids

It is shown that RTTN has an unrecognized function at the core of the translation machinery and is enriched in cycling first-trimester neural progenitors and physically associates with ribosome-biogenesis and RNA-processing factors.

A. Hadar, K. Draganova, V. Iyer et al. · 0 citations

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