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Author

Takehiro Okabayashi

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Review Open access Sep 2026

From Evidence to Value: Integrating Evidence-Based Medicine, Patient Safety, Quality Improvement, Learning Health Systems, and Value-Based Healthcare.

RATIONALE Evidence-Based Medicine (EBM) has strengthened clinical decision-making, but evidence alone cannot ensure that care is delivered safely, consistently, or in a manner that produces outcomes meaningful to patients. Patient safety, Quality Improvement (QI), Learning Health Systems (LHS), and Value-Based Healthca...

Takehiro Okabayashi, R. Inada, T. Imai et al. · 0 citations
Review Aug 2026

Metabolic Modulation for Liver Regeneration in Hepatocellular Carcinoma: From Biological Mechanisms to Precision Regenerative Medicine

Targeting metabolic pathways represents a promising strategy to enhance liver regeneration and integrating metabolic biomarkers and personalized interventions may improve perioperative outcomes in HCC patients undergoing hepatectomy.

Takehiro Okabayashi, Motoyasu Tabuchi, Teppei Tokumaru et al. · 0 citations
Review Sep 2026

Overcoming cancer resistance in pancreatic cancer: toward dynamic precision oncology

A Dynamic Precision Oncology (DPO) framework is proposed that extends conventional precision oncology beyond baseline molecular profiling by integrating longitudinal assessment of tumor genomics, circulating tumor DNA, CA19-9, imaging, radiomics, and clinical characteristics and summarizes emerging strategies for overc...

Takehiro Okabayashi, Motoyasu Tabuchi, Teppei Tokumaru et al. · 0 citations

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