Aug 2026
Rapid and efficient generation of human 8-cell-like cells for embryo modelling
Ri8CLC induction enables blastoid formation even in the absence of MEK inhibition, TGF-β/Activin/Activin/Nodal inhibition and exogenous LIF, revealing a developmental competence consistent with an early embryonic state and providing a tractable model for studying early human embryogenesis.
Arda Odabas, Sıla Unlu, Eren Ozturk et al.
· bioRxiv · 0 citations