Author

Tao Zhang

2 papers indexed here

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#protein folding Sep 2026

Glutamine-regulated VCP acetylation creates a proteostasis vulnerability in RB1-deficient tumor

RB1 deficiency defines an aggressive tumor state with limited therapeutic options. Osteosarcoma represents a clinically relevant model of RB1 deficient malignancy, as RB1 alterations are among the most frequent genomic events in this tumor type. However, the non cell cycle vulnerabilities created by RB1 loss remain inc...

Bing-Hui Yang, Ying Cao, Yi-Ning Tao et al. · bioRxiv · 0 citations

Open access Aug 2026

The PROM1+SMAD5+ Tumor-Initiating Subpopulation Shapes Premetastatic Niches through Spatial Multi-Omics Landscapes in HER2-Positive Breast Cancer

The microenvironmental regulation of breast tumor-initiating cells and its interactions with stromal cells have been clarified and provided new insights into precision therapy.

Hui-Jing Yin, Wei Wang, Jing Ge et al. · Cancer Communications · 0 citations