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Author

Tarun Kumar Upadhyay

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Open access Sep 2026

Development of nanoemulsion-based in situ gel formulation of escitalopram oxalate for intranasal delivery in depression therapy

The optimized nanoemulsion-based in situ gel demonstrated sustained drug release, enhanced nasal permeation, acceptable safety, and improved antidepressant efficacy and Pharmacodynamic evaluation showed significantly greater reduction in depressive-like behaviours than oral escitalopram solution.

Vahid Vikram Minglani, Meenakshi Patel, Tarun Kumar Upadhyay · 1 citation
Open access Jul 2026

Computational identification of novel antiviral leads against SARS-CoV-2 Mpro through systematic virtual screening and molecular dynamics study

The study identifies LY2784544 and Pimobendan as potential antiviral agents for Mpro, given their stability, strong binding energy (BE) profiles, and existing clinical data, these compounds warrant additional experimental validation to determine their potential efficacy against SARS-CoV-2.

M. Alam, Lina I. Alnajjar, Tarun Kumar Upadhyay et al. · 0 citations

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