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#graph neural networks Open access Oct 2026

Brain dynamics as outcome predictors of non-suicidal self-injury during SSRI treatment in adolescent depression: a 14-month longitudinal study

Abstract Non-suicidal self-injury (NSSI) represents a major health concern among adolescents with depression, yet no pharmacotherapies are specifically approved for NSSI. Selective serotonin reuptake inhibitors (SSRIs), commonly prescribed for adolescent depression, show inconsistent efficacy for NSSI, highlighting the...

Dan Qiao, Yujiao Wen, Vince D. Calhoun et al. · 0 citations
#gene editing Open access Oct 2026

Impacts of different SETD1A mutations and genetic backgrounds on human induced pluripotent stem cell-derived hippocampal neurons

Human induced pluripotent stem cells (hiPSCs) provide a translational platform to interrogate the impact of genetic risk factors for various disorders on human biology. It has been a common practice to engineer premature stop codons to model predicted loss-of-function mutations using isogenic hiPSCs, yet effects of mut...

Yan Hong, Ting Zhao, Qian Yang et al. · 0 citations

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