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Author

Toshiyuki Ishiba

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Review Aug 2026

De-escalation of perioperative systemic therapy for early breast cancer.

Current evidence and ongoing studies on treatment de-escalation across breast cancer subtypes are summarized and integration of molecular biomarkers with response-adapted strategies may further refine risk stratification and support personalized treatment approaches.

M. Ono, Y. Sagara, Toshiyuki Ishiba et al. · 0 citations
Open access Jul 2026

Usefulness of Prognostic Stage in High-Risk Early Luminal Breast Cancer

American Joint Committee on Cancer PS offers superior prognostic stratification compared to UICC AS in high-risk luminal breast cancer, and incorporation into clinical practice may enable more personalized treatment approaches, particularly when identifying candidates for adjuvant abemaciclib therapy.

Mio Adachi, Toshiyuki Ishiba, Takashi Kuwayama et al. · 0 citations

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