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The gut microbiome has emerged as a potential contributor to cardiovascular diseases (CVDs), including atherosclerosis, acute coronary syndrome (ACS), and peripheral arterial disease (PAD). While observational studies link dysbiosis to CVD, causal relationships remain uncertain.
Sepsis is a critical medical state considered a life-threatening response to infection, leading to extensive inflammation and potential organ dysfunction. This systematic review focuses on the therapeutic impact of baicalin on sepsis complications. METHODS This systematic review followed PRISMA guidelines and was reg...
Breast Cancer (BC) continues to be a predominant cause of cancer-related death globally, with clinical therapy impeded by off-target toxicity and limited therapeutic windows of traditional chemotherapeutics, especially across various molecular subtypes. This study critically assesses the integration of advanced nanocar...
The fundamental immunosuppressive interactions within the TME are discussed and subsequently it is examined how these agents enhance immune responses by reprogramming stromal and immune cells, as well as their secreted mediators within the TIME.
The regulatory mechanisms linking ferroptosis and the tumor immune microenvironment are highlighted, a critical discussion of recent developments in bionanomaterial‐based therapeutic platforms is provided, and the challenges and prospects for clinical application of these platforms for immunotherapy are outlined.
This review synthesizes available evidence indicating that several KIFs, specifically KIF4A, KIF14, KIF20A, and KIFC1, function as key oncogenic regulators and represent important prognostic biomarkers and therapeutic targets in bladder cancer.
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