Vicente J. Parot

Large-scale all-optical electrophysiology links excitability and connectivity to circuit dynamics in vivo

To understand neural computations, one would like to relate circuit dynamics to neuronal intrinsic excitability and connectivity. We developed tools for large-scale all-optical electrophysiology and applied them to approximately 300 layer 1 interneurons per mouse in vivo. Across two mice, targeted stimulation and volta...