Author

Wei-Hong Zhu

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Open access Sep 2026

Photoinduced cobalt-catalyzed enantioconvergent synthesis of 1,3-diamines via aziridine ring-opening addition

Chiral amines are privileged scaffolds with pervasive importance across the organic synthesis. Nevertheless, the stereoselective construction of 1,3-diamines bearing multiple stereocenters represents a significant and persistent challenge in synthetic chemistry. Addressing this, we recognized aziridines as ideal yet un...

Ting Xia, Ke-Jie Xu, Xiao-Cheng Zhang et al. · Science Advances · 0 citations

Open access Sep 2026

Kinetic assembly tuning NIR-II cyanine aggregated states: Remarkable photothermal-mediated sustained retention in orthotopic hepatoma

Conventional photothermal nanotheranostics suffer from fluorescence quenching caused by energy transfer between imaging and photothermal agents. Although unimolecular nanotheranostic systems circumvents the issue, it remains inadequate for generating substantial fluorescence and photothermal effects simultaneously unde...

Yue Wu, Mei-Ling Zhao, Meng-Lan Wu et al. · Science Advances · 0 citations

#protein folding Sep 2026

Discriminating Monomers and Fibrils of Amyloid-β1-42 With Site-Ordered Peptide-QMFluors.

The detection of soluble amyloid-β (Aβ), the most neurotoxic species in early Alzheimer's disease (AD), remains a major analytical challenge. Conventional probes are designed to target the β-sheet structures of mature fibrils and are thus blind to these transient, nonfibrillar species. Here, we introduce "site-ordered...

Rui-Long Dai, Jian-Feng Dai, Chen-Xu Yan et al. · Angewandte Chemie · 0 citations