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Review Open access Sep 2026

The oral–lung axis in lung cancer: microbial translocation, immune reprogramming, and clinical implications

The oral–lung axis describes microbial and inflammatory exchange between the oral cavity and the lower respiratory tract. Its relevance to lung cancer is supported by the detection of oral-associated taxa in lower-airway samples, epidemiological links between periodontal disease and lung cancer risk, and experimental e...

Xiang-Liang Liu, Guan-Ran Ding, Jin Lu et al. · 0 citations
Review Open access Aug 2026

Circulating tumor DNA in lung cancer immunotherapy: prognostic marker today, predictive tool tomorrow?

Circulating tumor DNA currently functions mainly as a prognostic and response-associated biomarker in lung cancer immunotherapy, while its predictive, decision-defining role remains an important but investigational objective.

Yan Li, Guan-Yu Lu, Wei Song et al. · 0 citations
Review Jul 2026

Pulmonary nodule prediction in the multi-omics era: integrating radiomics, AI, liquid biopsy, and airway classifiers.

The need for prospective validation and multidisciplinary collaboration to translate advances in radiomics, AI, liquid biopsy, airway classifiers, and multi-omics integration into clinically useful pathways that improve early lung cancer detection, reduce unnecessary interventions, and enhance patient outcomes is highl...

Yan Li, Guan-Yu Lu, Xiang-Liang Liu et al. · 0 citations

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