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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Wenhan Lu

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Clinical trial Open access Aug 2026

T cell receptor repertoire dynamics and newly identified functional regulators of autologous tumor-infiltrating lymphocyte therapy in advanced solid tumors

Tumor-infiltrating lymphocyte (TIL) therapy has demonstrated clinical potential in melanoma; however, its applicability across diverse solid tumors in Asian patients remains unclear. Identification of molecular targets to enhance the antitumor activity of TIL is urgently needed. In a phase I investigator-initiated tria...

Fen-Ge Li, Ji-Long Yang, Gregory A. Lizee et al. · 0 citations
#gene editing Open access Aug 2026

Genetic Engineering of Tumor‐Infiltrating Lymphocytes (TIL) via a T‐Editor Platform to Enhance Anti‐Tumor Activity

The T-Editor platform enables rapid and efficient CRISPR-mediated gene editing for engineering TIL to enhance its therapeutic potency and FAM84B may represent a novel potential target for improving TIL-mediated antitumor activity.

Fenge Li, Xuejiao Ma, Yongming Xue et al. · 0 citations

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