Author

Wenqiang Liu

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Open access Aug 2026

Decoding macrophage-driven tumor heterogeneity in renal cell carcinoma using spatial and single-cell transcriptomics

Highlights • A macrophage-associated prognostic signature was developed for KIRC.• Prognostic genes were identified through Cox analysis and multi-algorithm screening.• An MRCS classifier was independently constructed using SLC11A1 and IFI30.• Survival stratification and validation were systematically performed.

Jing-Jing Duan, Xiang-Lin Liu, Fangmei Zeng et al. · Translational Oncology · 0 citations

Jul 2026

AGTformer: Synergistic global transformer and adaptive graph gating for Accurate scRNA-seq clustering.

Single-cell RNA sequencing (scRNA-seq) enables transcriptomic profiling at single-cell resolution, but accurate identification of cell subpopulations remains challenging because of the high dimensionality, sparsity, and dropout effects of scRNA-seq data. Existing deep learning-based clustering methods have shown promis...

Yuanyuan Dang, Wenqiang Liu, Hao Li et al. · Computational biology and ch... · 0 citations