Author

William J. Greenleaf

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Open access Jul 2026

An encyclopedia of human enhancer–gene regulatory interactions

An encyclopedia of enhancer–gene regulatory interactions in the human genome is built, revealing global properties of enhancer networks, identifying differences in regulatory complexity across genes, and improving analyses linking noncoding variants to target genes and cell types for common, complex diseases.

A. Gschwind, Kristy S. Mualim, Alireza Karbalayghareh et al. · Nature · 5 citations

#gene editing Open access Aug 2026

RNA delivery to the corneal endothelium using charge-altering releasable transporters

A charge-altering releasable transporter (CART) that delivers RNA selectively to the corneal endothelium, a non-regenerative cell layer whose dysfunction underlies several blinding conditions and establishes CARTs as a platform for non-viral gene delivery to the eye, with the potential to treat corneal dystrophies and other vision disorders.

Sean K. Wang, Zhijian Li, Sahil H Shah et al. · Science Advances · 0 citations