STING-mediated JAK-STAT suppression drives CD4⁺ T cell dysfunction in aging people living with HIV-1
STING-mediated JAK-STAT suppression is identified as a novel mechanism of immune dysfunction in aging PLWH, proposing targeted STING inhibition as a potential therapeutic strategy to improve immune recovery in this vulnerable population.
Na Li, Hong-Yi Zheng, Xia Li et al.
· Immunity & Ageing · 0 citations