Author

Xianzhen Yin

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Review Open access Sep 2026

Host Genetic Susceptibility and Antiviral Immunity Shape the Pathogenesis and Outcomes of Herpes Simplex Encephalitis

Simple Summary Herpes simplex encephalitis (HSE) is the most common sporadic viral encephalitis worldwide. Even with antiviral therapy, it remains life-threatening and often leaves survivors with severe neurological deficits. Although herpes simplex virus (HSV) infection is extremely common, only a tiny fraction of inf...

Yu-Fei Zhan, Jing Li, Qiao-Ling Yuan et al. · Biology · 0 citations

#protein folding Aug 2026

Targeting viral proteins using insulin-like growth factor 2-fused lysosomal targeting chimera platform to combat viral infection.

Overall, iLYTAC converts non-neutralizing antibodies into functional degraders of viral proteins, enabling effective suppression of infection and providing a potential platform for broad-spectrum antiviral therapeutics.

Saiya Ma, Jie Zhang, Sijie Zhou et al. · International Journal of Bio... · 0 citations