Author

Xiang-Ping Xie

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#gene editing Review Open access Oct 2026

Why only 3 months? Immunological constraints on CAR-T therapy in gastrointestinal cancers

In June 2026, satri-cel/CT041, a chimeric antigen receptor (CAR) T-cell product targeting Claudin18.2, received approval from China’s National Medical Products Administration for the treatment of Claudin18.2-positive, HER2-negative advanced gastric/gastroesophageal junction adenocarcinoma after failure of at least tw...

Li-Ping Zeng, Sheng Wei, Nan Chen et al. · Frontiers in Immunology · 0 citations

Review Open access Aug 2026

Mitochondrial Metabolic Reprogramming and Skin Immune Homeostasis: From Basic Mechanisms to Therapeutic Perspectives

This review systematically examines the key mechanisms of mitochondrial metabolic reprogramming in skin immune disorders, focusing on 3 typical scenarios: the metabolic preferences of immune cells, mitochondrial DAMP-mediated autoinflammation, and the impact of mitochondrial dynamics imbalance on tissue-resident memory...

Nan Chen, Xiang-Ping Xie, Shuang-Yan He et al. · Immune Network · 0 citations