Author

Xiao-Dong Wang

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Review Open access Oct 2026

IFN‐γ‐Associated Signaling Networks in Interstitial Lung Disease Associated With Sjögren's Disease

ABSTRACT Background Sjögren's disease (SD) is a chronic systemic autoimmune disorder that can affect multiple organ systems. Interstitial lung disease (ILD) is a clinically significant pulmonary manifestation of SD and is associated with impaired quality of life and increased mortality. Interferon‐γ (IFN‐γ), a major ef...

Qian-Qian Chen, Yu-Han Li, Yi-Ming Chen et al. · Immunity, Inflammation and D... · 0 citations

Review Sep 2026

Subclinical inflammation and early pathogenesis of rheumatic diseases: mechanistic insights relevant to primary care.

The heterogeneity and compartmentalization of early immune activation explain why routine clinical assessment and standard inflammatory markers frequently fail to detect active disease in primary care and reframes diagnostic delay as a biologically driven phenomenon rather than a limitation of clinical practice.

Wen-Tong Wu, Ya-Jing Liu, Xiao-Dong Wang et al. · Irish Journal of Medical Sci... · 0 citations

Sep 2026

NAMPT activation protects against myocardial ischemia/reperfusion injury via FSP1-CoQ10 ferroptosis defense.

Findings identify the NAMPT-FSP1/CoQ10 axis as a potential metabolic target for myocardial protection against reperfusion injury and attenuates MIRI by restoring redox homeostasis and sustaining FSP1/CoQ10-mediated ferroptosis defense, likely through NAD(P)H-dependent metabolic coupling.

Xiao-Dong Wang, Chang Liu, Jie Wang et al. · Life Science · 0 citations