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Author

Xiao-Feng Zeng

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Oct 2026

Targeting mitochondrial morphofunctional homeostasis and oxidative stress: Iristectorigenin A protects against cardiac remodeling via SIRT6/FOXO1 signaling.

It is discovered that ITG inhibits oxidative stress and safeguards mitochondrial morphofunctional homeostasis in response to pathological stress through activating SIRT6/FOXO1 axis, suggesting the therapeutic potential of ITG in the treatment of cardiac hypertrophy and remodeling.

Jia-Hao Li, Dan Li, Fei-Xue Xu et al. · 0 citations

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