Author

Xiaohui Liao

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#gene editing Review Open access Sep 2026

Mitochondria‐Targeted Nanotherapeutics: A Promising Strategy in Modulating Mitochondrial Function, Transfer, and Transplantation

This review provides a structured synthesis that spans from the biological basis of mitochondrial function and transfer to the broad applications of nanomaterials in mitochondria‐targeted therapies, with a dedicated analysis of their roles in mitochondrial targeting, functional modulation, and gene editing.

Yuan-Yuan Su, Zhi-Yan Gong, Jiao Mu et al. · Advancement of science · 0 citations

Open access Jul 2026

LncPTEC mediated homocysteine accumulation elevates oxidative stress via UBQLN1-dependent MTHFD1 ubiquitination in DKD.

It is shown that homocysteine accumulation in proximal tubular epithelial cells (PTECs) is a significant contributor to mitochondrial oxidative stress in DKD and the role of the lncPTEC/MTHFD1 axis in Hcy-mediated mitochondrial oxidative stress is elucidated, offering potential diagnostic biomarkers and therapeutic tar...

Qi-Jia Wang, Tian-Hui Wu, Peilin Li et al. · Cell Death and Disease · 0 citations