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Author

Xiao-Jun Zhou

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Open access Oct 2026

tACS suppresses M1 polarization of microglia after spinal cord injury through the cGMP-PKG signaling pathway

Strategies for repairing spinal cord injury (SCI) emphasize blocking the shift of microglia to the pro-inflammatory M1 phenotype, lowering neuroinflammation, and fostering neuronal survival. The cGMP-PKG pathway modulates immune cell function by decreasing the secretion of pro-inflammatory elements such as IL-1β an...

Hai-Di Bi, Ke Huang, Xiao-Jun Zhou · 0 citations
Review Jul 2026

From matrix to nucleus: CD44 as a central regulator of inflammaging, autophagy, and tissue homeostasis

Evidence is synthesized that CD44, through its structural domains, isoform diversity, and proteolytic processing, integrates extracellular cues to modulate key pathways to modulate key pathways such as STAT3, NF-κB, and the class III PI3K complex.

Syeda Ayesha Ali, Peng-Fei Qiang, Xiaojun Zhou et al. · 0 citations

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