Author

Xiao-Qin Zhao

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Open access Sep 2026

Aerobic Exercise Ameliorates Renal Injury in High‐Fat Diet‐Fed Mice: A Novel Effect Mediated by the Drp1‐mtROS Pathway

Aberrant activation of dynamin‐related protein 1 (Drp1) promotes excessive mitochondrial reactive oxygen species (mtROS) production; however, whether the Drp1‐mtROS pathway mediates the renoprotective effects of aerobic exercise remains unclear.

Hui-Qian Ren, Hao-Feng Sun, Zhe-Ying Ma et al. · Acta Physiologica · 0 citations

Open access Aug 2026

Aerobic Exercise Attenuates High-Fat Diet-Induced Skeletal Muscle Atrophy by Suppressing Oxidative Stress, Inflammation, and Drp1-Associated Mitochondrial Fission

It is suggested that Drp1 phosphorylation and associated mitochondrial fission may contribute to the protective effects of aerobic exercise against HFD-induced skeletal muscle atrophy.

Yi-Wen Yuan, Zhen-Xian An, Min Hu et al. · Antioxidants · 0 citations

Jul 2026

Exercise training attenuates high-fat diet-induced skeletal muscle atrophy by inhibiting Drp1-mediated cuproptosis in male mice.

OBJECTIVE The present study investigated the role of Drp1 in cuproptosis and its underlying mechanisms, while examining the effects of aerobic exercise on high-fat diet-induced skeletal muscle atrophy. These findings may provide a theoretical basis for exercise interventions and targeted therapies for obesity-associate...

Min Hu, Yiwen Yuan, Zhenxian An et al. · Cellular Signalling · 0 citations