Open access
Aerobic Exercise Ameliorates Renal Injury in High‐Fat Diet‐Fed Mice: A Novel Effect Mediated by the Drp1‐mtROS Pathway
Hui-Qian Ren
Hao-Feng Sun
Zhe-Ying Ma
Qi Wang
Hui Yang
Xiao-Qin Zhao
Yu-Xiang Liu
Shou Pan
Zu-Jie Xu
Medicine
Abstract
Aberrant activation of dynamin‐related protein 1 (Drp1) promotes excessive mitochondrial reactive oxygen species (mtROS) production; however, whether the Drp1‐mtROS pathway mediates the renoprotective effects of aerobic exercise remains unclear.