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Xin-Bo Shi

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Open access Sep 2026

Integrated proteomic and metabolomic analysis reveals the mechanism of astragalus complanatus flavonoids against liver fibrosis in rats

Astragali Complanati Semen (ACS) is a traditional Chinese medicinal herb conventionally applied to tonify the liver and kidney. As the primary bioactive ingredients of ACS, Astragalus complanatus flavonoids (ACF) exert hepatoprotective and anti-fibrotic effects. This study aimed to elucidate the antifibrotic mechan...

Rui-Na Zhou, Yang Wang, Xin-Bo Shi et al. · 0 citations
Aug 2026

Multi-omics integration deciphered microbial and metabolite dynamics during flavor development of probiotic-fermented Gastrodia elata Blume.

This research provides a theoretical foundation for regulating specific flavors in GE by examining the succession of metabolites and microorganisms during the fermentation of Gastrodia elata Blume and their interrelationships.

Chao-Qi Zhang, Wenhao Liu, Xiaocui Meng et al. · 0 citations
Sep 2026

Single-Cell Transcriptomic Profiling of the O -Methyltransferase Characteristics of Flavonoid Biosynthesis in Ziziphus jujuba var. spinosa Fruit

The cellular architecture of flavonoid metabolism in sour jujube fruit is revealed, providing genetic resources for breeding varieties with enhanced flavonoid profiles to develop functional foods and nutraceuticals.

Guo-Long Li, Hong-Hong Jiao, Wan-Li Zhao et al. · 0 citations

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