Author

Xin-Yuan Zhao

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Sep 2026

Gut Microbiota-Associated Suppression of Intestinal β-Catenin Signaling Contributes to Barrier Dysfunction and Hepatic Pyroptosis Following SCCPs Exposure.

Short-chain chlorinated paraffins (SCCPs), as persistent organic pollutants, pose potential health threats, yet their toxicological mechanisms remain incompletely elucidated. This study demonstrates that exposure to SCCPs can induce liver injury in mice. Specifically, SCCPs interfere with the expression of intestinal t...

Dong-Lei Huang, Wen Zhang, Xiao Wang et al. · Toxicology · 0 citations

Review Aug 2026

ABCC6 in Cellular Metabolic Homeostasis: Biochemical Links to Extracellular Nucleotide Signaling, Mitochondrial Stress, and Senescence

This review integrates established mineralization biology with emerging metabolic evidence, focusing on the extracellular nucleotide–PPi pathway, downstream adenosine-related signaling, mitochondrial stress, lipid and cholesterol handling, and vascular complications.

Ling-Juan Yang, Fangsicheng Zhang, Yi-Lu Duan et al. · Cell Biochemistry and Biophy... · 0 citations

Open access Aug 2026

Circulating lipids, lipoproteins, and the risk of idiopathic pulmonary fibrosis: a cohort study and genetic analysis

Triangulating evidence across approaches, Mendelian randomization analyses supported inverse associations of genetically predicted total cholesteryl esters and sphingomyelins with IPF risk, and highlights cholesterol and sphingolipid metabolism as potential contributors to IPF susceptibility.

Jiahao Zhu, Yu-Hao Shen, Zhe-An Yan et al. · Journal of Lipid Research · 0 citations