Open access
Sep 2026
TopoFlow: Evolutionarily Conditioned Flow Matching for Protein Conformational Ensemble Generation
Xin-Guang Yang, Xin-Yue Cui, Xu-Hui Li et al.
· bioRxiv · 0 citations
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This study employed targeted genome editing to enable the biosynthetic production of spider silk proteins in silkworm silk gland bioreactors and provided a promising strategy for the biofabrication of silkworm-spider composite silk.
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