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Xiu-Li Liu

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Sep 2026

FTO-mediated GPX4 m6A modification in ferroptosis-induced DNA damage and inflammatory response during acute lung injury

Targeting the FTO-GPX4 axis may offer novel therapeutic strategies for ALI, and silencing FTO in vivo significantly ameliorates pulmonary tissue pathology, impaired lung function, ferroptosis, and inflammatory responses in mice, whereas GPX4 inhibition reverses this protective effect.

Xiu-Li Liu, Ying Gu, Fang Yuan · 0 citations

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