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#protein folding Oct 2026

CS-SelectFold: Chemical-Shift-Guided Selection of Protein Hidden Conformations from a Generative Protein Structure Model

Low-populated protein excited states can play decisive roles in function, ligand recognition, and misfolding, but their structural characterization remains difficult because these conformations are transient and sparsely populated. Here, we present CS-SelectFold, a framework that combines generative conformational sa...

Wan-Jia Tang, Qian-Qian Wang, Xiong-Jie Xiao et al. · 0 citations
Review Open access Aug 2026

Going high-throughput: Dynamic conformations and interactions in vivo

The integration of NMR and XL-MS establishes a powerful synergistic framework that bridges atomic-resolution local structures and large-scale interaction topologies, thereby enabling comprehensive characterization of protein dynamic conformations and interaction networks in native environments.

Zhou Gong, Qun Zhao, Min Sun et al. · 0 citations

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