Author

Xue-Ping Zeng

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Open access Sep 2026

The mitochondrial RNA extrusion-induced innate immunity is regulated by N6-methyladenosine machinery

In vitro models of mtRNA extrusion are established, and m6A-dependent modulation as a potential therapeutic target for mtRNA-driven inflammation is highlighted.

Qing Hu, Yi-Fei Zhang, Shi-Xuan Wang et al. · bioRxiv · 0 citations

Aug 2026

Self-exploding tumor microenvironment-responsive nanomedicine as "ROS Bomb" ignites STING pathway for triple-negative breast cancer immunotherapy.

It is reported that horseradish peroxidase (HRP) can catalyze artemisinin to generate ROS, and a "ROS bomb" nanomedicine was designed for antitumor immunotherapy, offering a potent approach for treating deep-seated tumors.

Ke-Qiang Lu, Yaoquan Su, Xing-Chen Zhou et al. · Journal of Controlled Releas... · 0 citations