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The mitochondrial RNA extrusion-induced innate immunity is regulated by N6-methyladenosine machinery

Qing Hu Yi-Fei Zhang Shi-Xuan Wang Xue-Ping Zeng Feng-Yu Wang Ting Fu Yue-Qing Chen Jia-Min Lyu Mijia Lu
Sep 2026 · bioRxiv · 0 citations · 51 references
Biology

TL;DR

In vitro models of mtRNA extrusion are established, and m6A-dependent modulation as a potential therapeutic target for mtRNA-driven inflammation is highlighted.

DOI Semantic Scholar
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