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Author

Yamei Tang

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Oct 2026

Trial of Endovascular Therapy for Mild Stroke with Large-Vessel Occlusion.

BACKGROUND Whether endovascular therapy benefits patients with mild acute ischemic stroke from large-vessel occlusion involving the anterior circulation is uncertain. METHODS We conducted a multicenter, open-label, randomized trial in China involving patients with acute ischemic stroke of mild clinical severity (defi...

Jian-Min Liu, Ting-Yu Yi, P. Xing et al. · 0 citations
Jul 2026

STAT6 Targets the Autophagy Pathway to Regulate Microglial Senescence in Cognitive Impairment Caused by Cerebral Small-Vessel Disease

Mechanistically, it was found that phosphorylated STAT6 (pSTAT6) enhanced autophagy, which reduced the burden of senescent microglia and thereby ameliorated CSVD-induced VCI, providing insights into the potential of targeting the STAT6 pathway in VCI associated with CSVD.

Xiaolu Liu, Qing Liu, Jingwen Yang et al. · 0 citations

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