Author

Yashwant Kumar

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Open access Sep 2026

Metabolic modeling with reverse mapping links host perturbations to Mycobacterium tuberculosis

Summary Understanding host-pathogen interactions during Mycobacterium tuberculosis (Mtb) infection has largely relied on identifying bacterial genes essential for intracellular survival. However, conventional reverse genetics approaches often overlook host pathways that regulate Mtb growth. Here, we developed a backtra...

Jayendrajyoti Kundu, Vishawjeet Barik, Abhijit Paul et al. · iScience · 0 citations

#protein folding Open access Sep 2026

Proteome-wide remodelling in Klebsiella pneumoniae during step-wise adaptive evolution against colistin

Short-duration exposure (SDE) of antibiotics is among the major drivers of the emergence of antimicrobial resistance (AMR) among bacterial pathogens. Klebsiella pneumoniae is a critical priority bacterial pathogen and rapidly acquiring MDR/XDR traits even against major antibacterial classes of antibiotics. Since colist...

Sevaram Singh, Lovnish Thakur, Sapna et al. · PLoS ONE · 0 citations