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Review Open access Oct 2026

Roles of endogenous retrovirus- and other LTR retrotransposon-derived proteins and peptides in neurological disorders, oncogenesis, and host defense.

LTR retrotransposons, including endogenous retroviruses (ERVs), constitute approximately 9% of the human genome and represent remnants of ancient mobile genetic elements. Although most of these sequences have accumulated truncations and mutations and have long been regarded as genomic relics, accumulating evidence indi...

Noi Saitoh, Ryo Yanagiya, Yi Cong et al. · 0 citations
Review 2026

Drug Discovery from Gene Expression/Gene Regulation.

This chapter explores the integration of AI-driven approaches in gene expression analysis, focusing on differential expression analysis, clustering techniques, and gene regulatory network (GRN) inference, and discusses the role of dimensionality reduction and unsupervised learning in identifying disease subtypes and pa...

Yi Cong, Toshinori Endo · 0 citations

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