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Yi-Di Sun

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Open access Aug 2026

The cellular and molecular basis of gyrus-sulcus specialization in the primate brain

How differences in brain cell composition help define cortical folds are uncovered and a link between microscopic cellular organization and large-scale brain networks in primates is revealed.

Ying-Guang Bai, Tao Song, He Wang et al. · 0 citations
Open access Jul 2026

CENO: A Genome-Scale World Model for Evolutionary Sequence Interpretation and Programmable Regulatory Design

CENO is introduced, a family of long-context generative genomic world models designed to preserve local DNA grammar while extending usable context to regulatory and chromatin scales and provides a genome-scale sequence world-model framework for sequence interpretation, evolutionary reasoning, gene-scale reconstruction...

Mingqian Ma, Yucheng Wu, Xin Chen et al. · 0 citations
Jul 2026

Full-length single-cell spatial transcriptomics reveals spatial and cell-type-specific transcript isoforms in the primate brain

Fullscope-seq resolved hundreds of major isoform switches across distinct brain regions and identified DTUs between superficial and deep cortical layers and showed substantial enrichment for neuropsychiatric disorder-associated genes.

Hengxin Liu, Yanhong Hong, Y. Zhang et al. · 0 citations

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