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Yi-Zhi Wang

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#gene editing Review Open access Sep 2026

CRISPRoff and CRISPRon Epigenetic Editing: Molecular Mechanisms and Therapeutic Applications

Epigenetic modification plays a key role in gene regulation. CRISPRoff and CRISPRon, based on Nuclease-dead Cas9 (dCas9), can achieve precise, reversible regulation of gene expression without changing the DNA sequence, which is better than traditional cutting technology. This article systematically compares the two set...

Yi-Zhi Wang · 0 citations

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