Pasteurella multocida (P. multocida) infection can induce severe pulmonary lesions in goats. However, little is known about the cellular changes in goat lungs caused by P. multocida. This exploratory study employs single-nucleus RNA sequencing (snRNA-seq) to systematically map the dynamic cellular landscape of caprine...
Qi An, Lianjie Liao, Haoju Pan et al.· Microbial Pathogenesis· 0 citations
Background The Ordos fine-wool sheep is a high-quality fine-wool breed in China, renowned for its excellent wool quality, meat production, and adaptability to the arid and semi-arid regions of Inner Mongolia. Body weight and wool traits are important economic characteristics in sheep breeding. This study aimed to ident...
Li-Fei Zhang, Ying Gu, Xiao-Long He et al.· Frontiers in Veterinary Scie...· 0 citations
Complex traits and disease phenotypes typically arise from the regulation of intricate genetic networks rather than single genes. Multiplex genome editing has therefore become central to trait engineering and therapeutic cell design. This review dissects the technological foundations and limiting factors of multiplex...
Lin-Li Wang, Yong-Bin Liu, Hong-Bing Han· Animal Research and One Heal...· 0 citations
A comprehensive overview of GS methodologies is provided, first covering the statistical foundations of linear mixed and Bayesian models, and then modern ML and DL approaches, to provide practical guidance for optimizing genomic evaluation strategies in the era of big data breeding.
Li-Fei Zhang, Mingzhu Zhang, Xinle Wang et al.· Journal of Animal Science an...· 1 citation
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