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Yong-Bin Liu

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Aug 2026

Single-nucleus transcriptomic atlas of the goat lung characterizes cell types associated with Pasteurella multocida infection.

Pasteurella multocida (P. multocida) infection can induce severe pulmonary lesions in goats. However, little is known about the cellular changes in goat lungs caused by P. multocida. This exploratory study employs single-nucleus RNA sequencing (snRNA-seq) to systematically map the dynamic cellular landscape of caprine...

Qi An, Lianjie Liao, Haoju Pan et al. · 0 citations
Open access Aug 2026

Genome-wide association study reveals candidate genes associated with body weight and wool traits in Ordos fine-wool sheep

Background The Ordos fine-wool sheep is a high-quality fine-wool breed in China, renowned for its excellent wool quality, meat production, and adaptability to the arid and semi-arid regions of Inner Mongolia. Body weight and wool traits are important economic characteristics in sheep breeding. This study aimed to ident...

Li-Fei Zhang, Ying Gu, Xiao-Long He et al. · 0 citations
#gene editing Review Open access Sep 2026

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Complex traits and disease phenotypes typically arise from the regulation of intricate genetic networks rather than single genes. Multiplex genome editing has therefore become central to trait engineering and therapeutic cell design. This review dissects the technological foundations and limiting factors of multiplex...

Lin-Li Wang, Yong-Bin Liu, Hong-Bing Han · 0 citations
Review Open access Aug 2026

From linear models to deep learning: statistical advances in genomic selection for animal breeding

A comprehensive overview of GS methodologies is provided, first covering the statistical foundations of linear mixed and Bayesian models, and then modern ML and DL approaches, to provide practical guidance for optimizing genomic evaluation strategies in the era of big data breeding.

Li-Fei Zhang, Mingzhu Zhang, Xinle Wang et al. · 1 citation

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