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#gene editing Review Open access Oct 2026

The advances and challenges of mRNA-LNP application in fields of hematology and oncology therapeutics

The rapidly global deployment of COVID-19 mRNA-LNP vaccines established the clinical feasibility of combining RNA medicine with LNP delivery systems, transforming a long-standing experimental concept into a scalable therapeutic modality, previously considered impossible. Currently, the value of mRNA-LNPs has been expan...

Yuan Wang, You Ge, Yu Chen et al. · 0 citations
Open access Jul 2026

Co-receptor usage in distinct phylogenetic clusters of HIV-1 CRF01_AE is associated with differential immune reconstitution after antiretroviral therapy

Comparing immune reconstitution after antiretroviral therapy (ART) between individuals infected with clusters 4a and 4b and to explore virological determinants underlying cluster-specific differences reveals that cluster 4a infection is associated with slower immune recovery and poorer clinical outcomes, likely be rela...

Yangyang Liu, Jing Lu, T. Qiu et al. · 0 citations

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