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Yuan-Qiang Zou

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Open access Sep 2026

Bacteroides cellulosilyticus-derived 2-hydroxyphenylacetic acid rectifies hepatic lipid homeostasis in MASLD by targeting the PPARγ-CD36 axis

The mechanism by which B. cellulosilyticus and 2HPAA alleviate MASLD by targeting the PPARγ-CD36 pathway is revealed, providing a new perspective for the study of gut microbiota-host interactions in regulating liver diseases.

Kaiwei Chen, Zizhen Yang, Ji-Xing Peng et al. · 0 citations
Review Open access Aug 2026

Promises and pitfalls of long-read sequencing for resolving microbial complexity

This review elucidates the impact of LRS across isolate genomics, metagenomics, and multi-omics domains and indicates that LRS is increasingly becoming the method of choice for isolate genomics and metagenomics.

Xing Rao, Yu-He Gu, Gabriella et al. · 0 citations
Open access Aug 2026

Complete genome-derived metabolic interactions reveal the impact of gut ecology on human health.

This work leverage 1,150 complete genomes to construct genome-scale metabolic models, demonstrating that draft assemblies introduce systematic artifacts and omit critical transport functions, and connects genome completeness with microbial ecological organization and provides a framework for linking metabolic interacti...

Yu-He Gu, Haoyu Wang, Jin-Long Yang et al. · 0 citations
Open access Jul 2026

Integrated Genomics and Phenotypic Analysis of Pediococcus pentosaceus BGI-N8 and Pediococcus acidilactici BGI-N9: Partial Evidence Suggesting In Vitro Probiotic Properties to Glycolipid Metabolism Regulation Potential

Genomic and phenotypic results supported the potentials of BGI-N8 and BGI-N9 as candidate probiotic strains with distinct complementary strengths in glycolipid regulation, providing a theoretical basis for their synergistic application.

Jia-Yi Ma, Zhihui Ma, Xinyu Yang et al. · 0 citations

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