Yue Wang

FASTPolicy: Fairness-aware spatio-temporal adaptive cooperative energy management of the multi-energy microgrid coalition

Deep-Learning-Driven Discovery and Engineering of Imine Reductase for the Efficient Synthesis of Chiral Opine Derivatives

The narrow amine donor scope of imine reductases (IREDs) limits their application in the synthesis of opine compounds. Herein, we report a machine learning (ML)-guided protein engineering strategy to address this limitation. An IRED from an unclassified Ensifer, IRED5, was identified through deep-learning-based scree...

Single-Molecule Studies Reveal That Water Starts to Protect Proteins Even at the ppm Level

A consensus established by extensive thermodynamic and structural studies of proteins and DNA is that water acts as an indispensable structural cofactor rather than a passive solvent for biomolecules. Nevertheless, it remains unclear whether trace water still exerts a stabilizing effect on proteins under ultradry con...