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Yujie Dong

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Aug 2026

ZNF143 suppresses mitophagy to drive MASLD progression by regulating SMURF1/TRPV1 axis

ZNF143 upregulation exacerbated MASLD progression by mediating TRPV1 ubiquitination and degradation through transcriptionally activating SMURF1, and its knockdown mitigated lipid accumulation and liver injury by activating hepatocyte mitophagy.

Mei Long, Kewei Tan, Yujie Dong · 0 citations

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