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Yujin Jeong

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#gene editing Sep 2026

Spacer-engineered donor DNA enhances CRISPR-Cas9-mediated knockin to establish a chemical knockdown platform for endogenous proteins.

A simple donor DNA engineering strategy that enhances HDR-mediated gene knockin by appending additional gRNA-recognizable spacer sequences to donor templates is investigated and established a readily implementable framework that integrates improved gene editing with on-demand chemical knockdown of endogenous proteins.

Seeun Jang, Siyoon Shin, Yujin Jeong et al. · 0 citations

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