Review
Aug 2026
Natural products mediate ferroptosis and immune microenvironment-linked sensitization in osteosarcoma: from chemotherapy resistance to combined therapeutic transformation.
This review summarizes the core molecular mechanisms of ferroptosis, focusing on the regulatory networks of Xc⁻-GSH-GPX4, Nrf2/HMOX1, p53, MAPK, and STAT3 pathways in osteosarcoma.
Yuwen Dai, Wanjun Ding
· Molecular diversity · 0 citations