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Z. Meng

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Open access Oct 2026

sDR5-Fc Administered Post-Exposure Alleviates Radiation-Induced Enteric Injury by Inhibiting ROS and NLRP3/Caspase-1/GSDMD-Dependent Pyroptosis and Inflammatory Response

Background: The risk of ionizing radiation exposure, including accidents and medical complications, has increased with the rapid development and broad application of nuclear technology. The intestine is highly susceptible to radiation, with radiation-induced intestinal injury characterized by a complex cascade of cellu...

Xuan Qiao, Shuang Guo, Zhuang Tian et al. · 0 citations
#protein folding Open access Sep 2026

Regulation of Intestinal P-Glycoprotein by Gamma-Ray Irradiation: Impacts on Transporter Expression and Oxidative Stress

P-glycoprotein (P-gp), a key efflux drug transporter which plays a pivotal role in the in vivo pharmacokinetics of medications, undergoes alterations in expression and function following radiation exposure that can impact drug metabolism and therapeutic efficacy. Current research has found that clinical doses of radiat...

Hai-Yang Wu, Jing Yang, Run-Tian Li et al. · 0 citations

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