Evidence from published clinical studies and 65 registered clinical trials on mRNA-based cancer vaccines are synthesized, summarizing key molecular principles, delivery strategies, clinical translation in solid tumors, and ongoing opportunities for future therapeutic development are summarized.
Zahraa A. Alkhafaje, M. H., Aniruddh Dash et al.· Current Research in Translat...· 0 citations
Taken together, anti-PD-1 scFvs represent a modular platform for localized checkpoint inhibition and potentially improved cost-effectiveness compared with systemic antibodies.
Zahraa A. Alkhafaje, H. Malathi, A. Dash et al.· Cancer Chemotherapy and Phar...· 0 citations
This review discusses how inherited variation in cytokine-regulatory pathways may influence IL-6, TNF-α, interferon, and TGF-β signaling, thereby contributing to inflammatory set points that favor chronic immune activation and inflammaging.
M. Alshahrani, Zahraa A. Alkhafaje, Uday Abdul-Reda Hussein et al.· Immunogenetics· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.