The gut–lung axis represents a predominantly gut-to-lung communication network through which gut microbiota and their metabolites influence pulmonary immunity. In asthma, gut dysbiosis—characterized by reduced microbial diversity, depletion of short-chain fatty acid (SCFA)-producing taxa, and expansion of pro-inflammat...
Feng-Xian Ni, Chun-Feng Pan, Hui-Hui Chen et al.· Frontiers in Immunology· 0 citations
Ovarian cancer remains the most lethal gynecologic malignancy, a status largely attributable to late-stage diagnosis and inevitable chemoresistance. The cGAS-STING pathway, a cornerstone of innate immune surveillance, has emerged as a critical nexus linking genomic instability to antitumor immunity—a connection of pa...
Hui-Hui Chen, Feng-Xian Ni, Dong-Hui Huang et al.· Frontiers in Immunology· 0 citations
It is argued that the cuproptosis-immune axis warrants systematic exploration as a potential target for disease-modifying therapy, while acknowledging the substantial hurdles that must be overcome before clinical translation can be contemplated.
Feng-Xian Ni, Jie Hu, Pei-sheng Chen et al.· International Immunopharmaco...· 0 citations
Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome characterized by persistent oxidative stress and maladaptive immune responses, rather than a single disease entity. Oxidative stress not only damages lung tissue but also reprograms immune cells through both classical epigenetic mechanisms (DNA me...
Chun-Feng Pan, Qiong Wan, Feng-Xian Ni et al.· Frontiers in Immunology· 0 citations
The bidirectional metabolism-m6A crosstalk as a theoretical framework requiring experimental validation, and single-cell m6A sequencing, spatial metabolomics, and CRISPR screening as tools to accelerate precision TCM for COPD are outlined.
Hui-Hui Chen, Feng-Xian Ni, Dong-Hui Huang et al.· Frontiers in Immunology· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
