Zhen-Xi Guo

Nanoconfined Protein Scaffold as a Generalizable Platform Empowers Synergistic Enzyme–Nanozyme Catalysis for Cascade Biotransformation

Enzymatic and chemoenzymatic cascades hold immense potential for industrial applications but are hindered by inherent instability, low atom economy, inefficient intermediate transfer, and complex enzyme immobilization processes. Here, we repurpose encapsulin, which naturally loads cargo, as a programmable nanoreactor...